Welcome to Cytoinnovations Ltd

Cytonic products are revolutionary formulas specifically engineered to fortify your body's trillions of cells, more specifically the cells of your immune system.

Cytonic - Cyto (cell) + Tonic (elixir).  Cytonics are powerful, natural health products containing Vitamin D Transport Protein (VDTP), a glycoprotein sometimes referred to as GcMAF.

We consume proteins everyday - they help to keep us strong & healthy. Cytonic products contain the specific protein required to feed our immune cells, VDTP. In our ISO and GMP registered laboratory, we extract VTDP from bovine colostrum and then filter it many, many times until only the proteins remain—there is absolutely no casin present.

Let us take a look at what cytonic products comprise of and how they regulate immune system function.

Cytoproteins (cyto meaning cell) are proteins that activate cells. There are 482 cytoproteins on the vitamin D transport protein chain and each activates a specific type of cell in our body.  Feeding our immune cells is one very important function of Cytoproteins, another major function is the transport of vitamins & fatty acids to build and repair cells as well as removing toxins from the body. This vital function earns the name 'transport protein'

What is a transport protein?

Transport proteins are involved in the movement of ions and micro- and macromolecules across biological membranes (i.e., a cell wall). Transport proteins are integral membrane proteins, meaning they exist within and span the membrane across which they transport substances. A very straightforward example of a transport protein in action would be hemoglobin picking up oxygen and transporting it to the tissues where it is needed.

Vitamin D Transport Protein is a multifunctional transport protein produced by the human body. It is responsible for transporting vitamin D, binding fatty acids, removing toxins, and a range of other roles associated with immune system modulation and inflammatory responses. It contains 482 cytoproteins interwoven into 3 domains with 3 important functions.

Domain 1. Vitamin D binding

Vitamin D promotes calcium absorption, modulates cell growth, contributes to neuromuscular and immune function, and reduces inflammation. Every cell in our body has a vitamin D receptor, and every cell in our body secretes a vitamin D hormone. Vitamin D transport protein binds the vitamin D already stored in the body and transports it to where it is most needed.

Domain 2. Fatty acid binding

Fatty acids are required for many vital human body functions from building healthy cells to maintaining brain and nerve function. Because our bodies can’t produce all the fatty acids we require, we must receive some of them through food. VDTP binds these essential fatty acids and transports them to where they can help our cells heal and repair.

Domain 3. Actin Scavenger

VDTP is an important component of the plasma actin scavenger system and acts like a refuse collector transporting these toxins from the lymphatic system, blood stream, tissues, and bones to the liver so that they can be naturally eliminated from the body.

Within this 3rd domain of VDTP functions, we find a cluster of cytoproteins designed to activate our immune cells. It is this cluster that first drew the attention of renowned immunologist Dr. Nobuto Yamamoto, who discovered that this specific cluster is responsible for activating our white blood cells into becoming natural killer cells, B-cells, and macrophages.

Inactive immune cells

Without VDTP, these three types of immune cells consume just enough energy to stay alive. In a healthy body, lymphocytes and monocytes release the enzymes needed to remove and digest the sugars produced by VDTP, to ultimately mature into what is collectively called our immune system. This process should be taking place inside you and I millions of times a day. If, for whatever reason, our lymphocytes and monocytes are not actvated, our immunity becomes compromised and is in danger of collapsing completely.
   

Natural Killer cells

Natural Killer cellsNatural Killer cells begin their lives as lymphocytes and mature in the lymph nodes. When we feel our glands are swollen, it is because our bodies are producing more natural killer immune cells. After about 72 hours, they are ready to leave the lymphatic system and enter the bloodstream. Once activated by vitamin D transport protein, they mature into natural killer cells, which are largely responsible for apoptosis (programmed cell death) of cancer cells and infected cells in the body. They are ruthless and ninja like in their actions. The generally accepted half life of natural killer cells is 7-10 days.
   

B-cells

 
B-cells

B-cells also begin their lives as lymphocytes and require vitamin D transport protein to fully mature. However, they behave very differently from natural killer cells. B-cells produce and release antibodies into the blood that attach themselves to specific pathogens, preventing them from entering cells and multiplying.

They also act as a beacon, signalling danger to natural killer cells. B-cells prevent cells from becoming infected, but if they do become infected, natural killer cells move in and destroy the infected cell. This leads us onto our 3rd, and most potent immune cell—the macrophage.

   

Macrophages

 
Macrophages

Macrophages are big and smart white blood cells that chase, capture, engulf, and digest intruders. They trap and phagocytize (literally, “eat”) their enemies. They can multiply rapidly when necessary. However, they’re naturally indolent and need to be activated by VDTP.

Opsonin “super glue” helps them stick to their prey. Their electron-driven free radical death ray (AKA “oxidative burst”) blasts holes in microbes and cancer cells. Once a microbe or cancer cell has been phagocytized by a macro, it is encapsulated inside a “phagolysosome” (the intracellular “death chamber”), where it is then killed (if it isn’t dead already).

The phagolysosome then secretes a cocktail of corrosive free radicals and enzymes that rapidly digest the pathogen down into its component parts conisting of amino acids, nucleic acids & fatty acids. Because these are fundamental cellular building blocks, the body quickly recycles them using the “spare parts” to build brand new healthy cells.

   

Nagalase – a little known enemy of the immune system

Nagalase

Before Dr. Yamamoto’s research on nagalase, immunosuppression caused by viruses and tumors was poorly understood. Yamamoto discovered that cancer patients had high levels of nagalase, and that this enzyme destroyed (deglycolylated) the cluster of cytoproteins on the VDTP chain required to activate our immune cells. Nagalase has no natural enemies, and no bodily process, drug, or treatment could outsmart it. Dr. Yamamoto’s research on this enzyme has led to our modern-day understanding of what causes immunosuppression, allowing cancers to grow and viruses to multiply unchecked.

Without access to this cluster of cytoproteins, which is found only on VDTP, activation of natural killer cells, B- cells, and macrophages is nearly impossible. Therefore, Dr Yamamoto began to focus on finding a way to outsmart nagalase.

Before Dr. Yamamoto’s research on nagalase, immunosuppression caused by viruses and tumors was poorly understood. Yamamoto discovered that cancer patients had high levels of nagalase, and that this enzyme destroyed (deglycolylated) the cluster of cytoproteins on the VDTP chain required to activate our immune cells. Nagalase has no natural enemies, and no bodily process, drug, or treatment could outsmart it. Dr. Yamamoto’s research on this enzyme has led to our modern-day understanding of what causes immunosuppression, allowing cancers to grow and viruses to multiply unchecked.

Without access to this cluster of cytoproteins, which is found only on VDTP, activation of natural killer cells, B- cells, and macrophages is nearly impossible. Therefore, Dr Yamamoto began to focus on finding a way to outsmart nagalase.

   

Finding Immunity from Nagalase

Dr Yamamoto's pursuit of negalase proved that it was in fact possible to prevent nagalase from destroying the protein cluster responsible for activating our immune cells. Through the application of various enzymes, he was able to remove two of the specific cytoproteins from this cluster and leave only the cytoprotein responsible for activating macrophages on the surface of VDTP. As a result, nagalase could no longer deactivate the protein and prevent it from activating macrophages. Dr. Yamamoto called his formula GcMAF—glucose macrophage activating factor—and he found that its application increased activation of macrophages for the benefit of immune system function.
   

The first human trials of GcMAF

The first human trials of GcMAF

In his first human trial to observe the effects of GcMAF, Yamamoto selected 30 patients with Stage 4 cancer. (ref needed here) The patients had previously received chemotherapy, radiotherapy, and/or surgery. Despite allopathic intervention all experienced elevated levels of nagalase in their blood, indicating that the cancer was returning. Throughout the trial, patients received 100ng (nanograms) of injectable GcMAF per week for no longer than 6 months. By the end of the trial, all patients were showed nagalase levels within the normal range, and 7 years post trial all 30 patients were reported to be alive and tests found that their nagalase levels remained within the normal range.

A few years later Dr. Yamamoto repeated this trial of injeted GcMAF with patients who were HIV positive; these patients also showed elevated levels of nagalase. By the end of the trial, negalase levels in all patients were also found within the normal range, giving injectable GcMAF a very positive track record.

Despite this revolutionary approach to stimulating immune system function and three successful human trials to support his theories, Dr. Yamamoto’s work had not received the accolades or even attention that it deserved. As a means of protecting his work, Yamamoto patented the process of GcMAF production and the nagalase test. He could not, however, patent VDTP because it is a naturally occurring protein or its derivative GcMAF.

   

Dr. Bradstreet’s pioneering work with GcMAF and autism

Dr. Bradstreet

The late Dr. Jeffrey Bradstreet was a dedicated doctor and researcher of successful biomedical interventions for children on the autism spectrum. In 2011, he began researching the work of Dr. Yamamoto and through nagalase testing he discovered that the children on the autism spectrum that he tested showed elevated nagalase levels. His next step was to take a small group of 20 children and administer injectable GcMAF. Follow-up blood testing showed decreased levels of nagalase along with positive anecdotal evidence from parents who reported improvements in cognition, socialization, health, and in some cases speech.

A subsequent study with more participants showed equally positive results. Click the link below to view the complete study.

http://vdbp.info/13/66-initial-observations-of-elevated-nagalase-activity-associated-with-autism-and-observed-reductions-from-gcmaf.html

   

The evolution of GcMAF to Cytonics

Cytoinnovations Ltd. has been researching and developing GcMAF products since 2011. In 2015, we tasked our scientists with the goal of using GcMAF to engineer VDTP to function, not only to activate monocytes into becoming macrophages, but also to activate our lymphocytes - all in the presence of nagalase. This, we hoped, would facilitate quicker responses by lymphocytes and more harmonious immune function overall.

Although macrophages are probably our most versatile immune cells, they are not as effective against viruses as our natural killer cells or B-cells. When natural killer cells and macrophages are activated together, macrophages revert to a secondary role, cleaning the battlefield of dead pathogens and cancer cells and then recycling their components to build new healthy cells. For this and several other reasons, we believed that splicing the protein cluster responsible for macrophage activation would lead to a product that would be far more effective than the original GcMAF, and we weren’t disappointed.

The two resulting protein structures, which are present in all cytonic products, allow for the activation of not only macrophages, but also natural killer cells and B-cells, a truly radical upgrade. In addition, because nagalase is localized to the blood, transdermal cytonic products (e.g., creams and oils) provide a faster, more efficient route toward propagating lymphocytes and ultimately faster elimination of pathogens, toxins, and tumors.